During World War II it was extensively used to combat fatigue and increase alertness in soldiers. In 1937, it became available in tablet form. Alles was part of a group of researchers looking for an ephedrine substitute. No pharmacological use was found for amphetamine until 1927, when pioneer psychopharmacologist Gordon Alles resynthesized it.
Amphetamine mechanism of action series#
It was one of a series of compounds related to the plant derivative ephedrine, which had been isolated from Ma-Huang that same year by Nagayoshi Nagai. He named the compound phenylisopropylamine. The name is also used to refer to the class of compounds derived from amphetamine, often referred to as the substituted amphetamines.Īmphetamine was first synthesized in 1887 by Lazar Edeleanu at the University of Berlin. The name amphetamine is derived from its chemical name: alpha-methylphenethylamine. The drug is also used illegally as a recreational club drug and as a performance enhancer. Brand names of the drugs that contain amphetamine include Adderall and Dexedrine. Initially it was more popularly used to diminish the appetite and to control weight. The molecular formula for the Ampetamine molecule is C9H13N.Īmphetamine Molecule ->in 3D with Jsmol
It is also used to treat symptoms of traumatic brain injury and the daytime drowsiness symptoms of narcolepsy and chronic fatigue syndrome. Amphetamine is a prescription CNS stimulant commonly used to treat attention-deficit hyperactivity disorder (ADHD) in adults and children.
0 kommentar(er)
